Marie choates foot disease
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Charcot-Marie-Tooth disease CMT refers to a group of disorders that affect the peripheral nervous system. The peripheral nerves carry signals from the brain to the muscles to move and sensory information from the rest of the body to the brain. CMT causes nerve fibers or their protective coat around them to degrade. Caring for the hands and feet can help alleviate some symptoms of the disease and prevent complications.
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Charcot's Foot (Charcot's arthropathy or neuroarthropathy)
Charcot-Marie-Tooth (CMT) < Neurology
Charcot-Marie-Tooth disease and the related disorders hereditary motor neuropathy and hereditary sensory neuropathy, collectively termed CMT, are the commonest group of inherited neuromuscular diseases, and they exhibit wide phenotypic and genetic heterogeneity. CMT is usually characterized by distal muscle atrophy, often with foot deformity, weakness and sensory loss. In the past decade, next-generation sequencing NGS technologies have revolutionized genomic medicine and, as these technologies are being applied to clinical practice, they are changing our diagnostic approach to CMT. In this Review, we discuss the application of NGS technologies, including disease-specific gene panels, whole-exome sequencing, whole-genome sequencing WGS , mitochondrial sequencing and high-throughput transcriptome sequencing, to the diagnosis of CMT.
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Charcot-Marie-Tooth Disease (CMT)
Back to Charcot-Marie-Tooth disease. The symptoms of Charcot-Marie-Tooth disease CMT can differ from person to person, even among relatives with the condition. Symptoms can vary depending on the type of CMT, and even people with the same type can experience it differently.
This damage is mostly in your arms and legs peripheral nerves. Charcot-Marie-Tooth disease is also called hereditary motor and sensory neuropathy. Charcot-Marie-Tooth disease results in smaller, weaker muscles.
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